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Traversing the Intricacies of Cannabinoids: A Comprehensive Expedition

Jason King • Mar 22, 2024

The Captivating World of More than 100 Cannabinoids

Traversing the Intricacies of Cannabinoids: A Comprehensive Expedition


In the vast expanse of cannabinoid science, a myriad of chemical compounds derived from the cannabis plant await exploration. From the renowned THC and CBD to the lesser-known CBG, CBN, and CBC, each cannabinoid contributes to the complex interplay of effects and applications associated with cannabis. Join us as we embark on a comprehensive journey through the labyrinthine landscape of cannabinoids, uncovering their roles, forms, and safety considerations while delving into the extensive lexicon of cannabis-related keywords.


Unveiling the Multifaceted World of Cannabinoids


Cannabinoids, the diverse molecules found within the cannabis plant, interact with the body's endocannabinoid system, influencing an array of physiological processes. While THC and CBD often command attention, a plethora of other cannabinoids contribute to the pharmacological effects and potential benefits of cannabis.


Major Cannabinoids:


  • Delta-9-Tetrahydrocannabinol (THC): Renowned for its psychoactive effects, THC interacts with cannabinoid receptors in the brain, leading to altered perception and cognition.
  • Cannabidiol (CBD): Non-intoxicating and celebrated for its potential therapeutic benefits, CBD exhibits anti-inflammatory and analgesic properties, making it a promising candidate for pain relief and neuropathic pain management.


Minor Cannabinoids:


  • Cannabigerol (CBG): Often present in low concentrations, CBG serves as a precursor to THC and CBD, potentially offering neuroprotective effects and contributing to pain relief.
  • Cannabinol (CBN): Formed through THC degradation, CBN is associated with sedative effects and may play a role in sleep regulation and chronic pain management.
  • Cannabichromene (CBC): Non-intoxicating and underexplored, CBC exhibits anti-inflammatory and analgesic properties, suggesting therapeutic benefits for pain relief and neuropathic pain.


Natural vs. Synthetic Cannabinoids:


While natural cannabinoids are derived from the cannabis plant, synthetic cannabinoids are laboratory-created compounds designed to mimic their effects. Synthetic cannabinoids, such as HU-210 and JWH series, may exhibit enhanced potency but also pose a higher risk of adverse effects due to variations in chemical structure and pharmacological activity.


Forms and Consumption Methods


Cannabinoids are available in various forms, catering to diverse preferences and consumption habits. Whether seeking immediate relief or sustained effects, individuals can choose from a multitude of options tailored to their needs and circumstances.


Traditional Consumption Methods:


  • Smoking and Vaporization: Inhaling cannabis flower or concentrates for rapid onset of effects and customizable dosing.
  • Edibles and Beverages: Consuming cannabinoid-infused food products or beverages for prolonged and discreet effects.


Alternative Delivery Mechanisms:


  • Topicals: Applying cannabinoid-infused creams, balms, or patches directly to the skin for targeted relief from pain and inflammation.
  • Sublingual Tinctures: Administering concentrated cannabinoid extracts under the tongue for rapid absorption into the bloodstream.


Novel Delivery Systems:


  • Transdermal Patches: Delivering cannabinoids through the skin for controlled and sustained release over time.
  • Suppositories: Rectal or vaginal administration for rapid absorption and bypassing of the digestive system.


Effects and Safety Considerations


Understanding the effects and potential risks associated with cannabinoid use is essential for promoting responsible consumption and minimizing adverse outcomes. While cannabinoids offer a range of therapeutic and recreational benefits, they also pose certain safety considerations that warrant attention and awareness.


Pharmacological Effects:


  • Psychoactivity: THC-induced euphoria and altered perception contribute to its recreational appeal but may also lead to adverse psychological effects.
  • Anti-inflammatory and Analgesic Effects: CBD and other cannabinoids exhibit anti-inflammatory and analgesic properties, offering potential benefits for pain relief and neuropathic pain management.


Safety Precautions:


  • Adverse Effects: Synthetic cannabinoids and high doses of THC may lead to adverse effects, including anxiety, paranoia, and cognitive impairment.
  • Individual Sensitivities: Variations in cannabinoid sensitivity and metabolism may influence individual responses, highlighting the importance of personalized dosing and monitoring.
  • Dependence and Tolerance: Prolonged use of cannabinoids, particularly THC, may lead to dependence and tolerance, necessitating caution and moderation.


Seeking Support and Assistance


For those grappling with cannabinoid misuse or seeking guidance on responsible consumption, various resources and support networks are available. Whether seeking confidential counseling or educational materials, individuals can access assistance tailored to their needs and circumstances.


Clinical Trials and Systematic Reviews:


  • Medical Cannabis Research: Ongoing clinical trials and systematic reviews evaluate the efficacy and safety of cannabinoids for various medical conditions, including chronic pain, forms of epilepsy, and neuropathic pain.


National Helplines:


  • National Alcohol and Other Drug Hotline: Providing free and confidential advice, information, and counseling for individuals experiencing substance-related concerns.


Conclusion: Navigating the Cannabinoid Odyssey


As our understanding of cannabinoids continues to evolve, so too does our appreciation for the complex interplay of chemical compounds and biological systems. From the psychoactive effects of THC to the therapeutic potential of CBD and beyond, cannabinoids offer a diverse array of effects and applications. By exploring the roles of cannabinoids in health and wellness, we gain insight into their multifaceted nature and potential therapeutic benefits. Through responsible consumption practices and informed decision-making, individuals can harness the benefits of cannabinoids while minimizing potential risks. Together, let us embark on a journey of exploration and discovery, navigating the intricate landscape of cannabinoids with curiosity, caution, and compassion.


Servant's Heart Natural Well-Being Products


Please visit Servant's Heart Products servantsheartglobal.com for THC-free, all-natural, affordable, high quality, and potent CBD products, including gummies and topical.


Additional Resources About Cannabinoids:


https://archive.org/details/cannabinoidshand00pert

https://nida.nih.gov/publications/research-reports/marijuana/how-does-marijuana-produce-its-effects

https://nida.nih.gov/publications/research-reports/marijuana/what-marijuana

http://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1962-01-01_3_page005.html

https://www.unodc.org/LSS/SubstanceGroup/Details/ae45ce06-6d33-4f5f-916a-e873f07bde02

https://unodc.org/LSS/SubstanceGroup/Details/ae45ce06-6d33-4f5f-916a-e873f07bde02

https://www.worldcat.org/issn/1520-6025

https://www.worldcat.org/issn/2578-5125

https://www.worldcat.org/issn/0362-4331

https://www.worldcat.org/issn/2050-3245

https://pubmed.ncbi.nlm.nih.gov/21305906

https://pubmed.ncbi.nlm.nih.gov/22325079

https://pubmed.ncbi.nlm.nih.gov/12446537

https://pubmed.ncbi.nlm.nih.gov/17931597

https://pubmed.ncbi.nlm.nih.gov/16636640

https://pubmed.ncbi.nlm.nih.gov/15451779

https://pubmed.ncbi.nlm.nih.gov/6271827

https://pubmed.ncbi.nlm.nih.gov/22290123

https://pubmed.ncbi.nlm.nih.gov/19689331

https://pubmed.ncbi.nlm.nih.gov/19349314

https://pubmed.ncbi.nlm.nih.gov/19924114

https://pubmed.ncbi.nlm.nih.gov/18589404

https://pubmed.ncbi.nlm.nih.gov/22532560

https://pubmed.ncbi.nlm.nih.gov/4609532

https://pubmed.ncbi.nlm.nih.gov/22150622

https://pubmed.ncbi.nlm.nih.gov/15866551

https://pubmed.ncbi.nlm.nih.gov/17157290

https://pubmed.ncbi.nlm.nih.gov/20829306

https://pubmed.ncbi.nlm.nih.gov/19693792

https://pubmed.ncbi.nlm.nih.gov/12373420

https://pubmed.ncbi.nlm.nih.gov/21838843

https://pubmed.ncbi.nlm.nih.gov/20357305

https://pubmed.ncbi.nlm.nih.gov/12586720

https://pubmed.ncbi.nlm.nih.gov/2848184

https://pubmed.ncbi.nlm.nih.gov/1470919

https://pubmed.ncbi.nlm.nih.gov/1470919

https://pubmed.ncbi.nlm.nih.gov/3529128

https://pubmed.ncbi.nlm.nih.gov/19949195

https://pubmed.ncbi.nlm.nih.gov/21481098

https://pubmed.ncbi.nlm.nih.gov/21484568

https://pubmed.ncbi.nlm.nih.gov/15173844

https://pubmed.ncbi.nlm.nih.gov/19609589

https://pubmed.ncbi.nlm.nih.gov/22310034

https://pubmed.ncbi.nlm.nih.gov/18691604

https://pubmed.ncbi.nlm.nih.gov/19124693

https://pubmed.ncbi.nlm.nih.gov/16506412

https://pubmed.ncbi.nlm.nih.gov/14660135

https://pubmed.ncbi.nlm.nih.gov/9823341

https://pubmed.ncbi.nlm.nih.gov/17551355

https://pubmed.ncbi.nlm.nih.gov/17551355

https://pubmed.ncbi.nlm.nih.gov/18021759

https://pubmed.ncbi.nlm.nih.gov/15574485

https://pubmed.ncbi.nlm.nih.gov/12037135

https://pubmed.ncbi.nlm.nih.gov/11160626

https://pubmed.ncbi.nlm.nih.gov/15277313

https://pubmed.ncbi.nlm.nih.gov/22178458

https://pubmed.ncbi.nlm.nih.gov/4713005

https://pubmed.ncbi.nlm.nih.gov/4609777

https://pubmed.ncbi.nlm.nih.gov/10454705

https://pubmed.ncbi.nlm.nih.gov/19961570

https://pubmed.ncbi.nlm.nih.gov/16796380

https://pubmed.ncbi.nlm.nih.gov/18262573

https://pubmed.ncbi.nlm.nih.gov/2165569

https://pubmed.ncbi.nlm.nih.gov/7632625

https://pubmed.ncbi.nlm.nih.gov/7605349

https://pubmed.ncbi.nlm.nih.gov/11106779

https://pubmed.ncbi.nlm.nih.gov/5879214

https://pubmed.ncbi.nlm.nih.gov/12427829

https://pubmed.ncbi.nlm.nih.gov/17662880

https://pubmed.ncbi.nlm.nih.gov/15840405

https://pubmed.ncbi.nlm.nih.gov/24934539/

https://pubmed.ncbi.nlm.nih.gov/16078824

https://pubmed.ncbi.nlm.nih.gov/26836472

https://pubmed.ncbi.nlm.nih.gov/32646718

https://pubmed.ncbi.nlm.nih.gov/29449262

https://pubmed.ncbi.nlm.nih.gov/16968947

https://pubmed.ncbi.nlm.nih.gov/15866316

https://pubmed.ncbi.nlm.nih.gov/10476817

https://pubmed.ncbi.nlm.nih.gov/10082303

https://pubmed.ncbi.nlm.nih.gov/7556170

https://pubmed.ncbi.nlm.nih.gov/21295074

https://pubmed.ncbi.nlm.nih.gov/32259074

https://pubmed.ncbi.nlm.nih.gov/15266552

https://pubmed.ncbi.nlm.nih.gov/11248677

https://pubmed.ncbi.nlm.nih.gov/25667194

https://pubmed.ncbi.nlm.nih.gov/17712814

https://pubmed.ncbi.nlm.nih.gov/17876302

https://pubmed.ncbi.nlm.nih.gov/16258853

https://pubmed.ncbi.nlm.nih.gov/23108553

https://pubmed.ncbi.nlm.nih.gov/26852073

https://pubmed.ncbi.nlm.nih.gov/9379442

https://pubmed.ncbi.nlm.nih.gov/33356248

https://pubmed.ncbi.nlm.nih.gov/16402100

https://pubmed.ncbi.nlm.nih.gov/34468204

https://pubmed.ncbi.nlm.nih.gov/18289087

https://pubmed.ncbi.nlm.nih.gov/17262436

https://pubmed.ncbi.nlm.nih.gov/17252329

https://pubmed.ncbi.nlm.nih.gov/17252329

https://pubmed.ncbi.nlm.nih.gov/22525682

https://pubmed.ncbi.nlm.nih.gov/19897346

https://pubmed.ncbi.nlm.nih.gov/18574142

https://pubmed.ncbi.nlm.nih.gov/25433633

https://pubmed.ncbi.nlm.nih.gov/30397641

https://pubmed.ncbi.nlm.nih.gov/24160757

https://pubmed.ncbi.nlm.nih.gov/27341312

https://pubmed.ncbi.nlm.nih.gov/11157422

https://pubmed.ncbi.nlm.nih.gov/21749363

https://pubmed.ncbi.nlm.nih.gov/36516885

https://pubmed.ncbi.nlm.nih.gov/28293911

https://pubmed.ncbi.nlm.nih.gov/18728714

https://pubmed.ncbi.nlm.nih.gov/36971760

https://pubmed.ncbi.nlm.nih.gov/22524785

https://pubmed.ncbi.nlm.nih.gov/16266285

https://pubmed.ncbi.nlm.nih.gov/10462059

https://pubmed.ncbi.nlm.nih.gov/8751435

https://pubmed.ncbi.nlm.nih.gov/10444099

https://pubmed.ncbi.nlm.nih.gov/9285589

https://pubmed.ncbi.nlm.nih.gov/11588122

https://pubmed.ncbi.nlm.nih.gov/11259648

https://pubmed.ncbi.nlm.nih.gov/12787057

https://pubmed.ncbi.nlm.nih.gov/11042139

https://doi.org/10.3390%2Fbiom11101411

https://doi.org/10.1021%2Fjm058183t

https://doi.org/10.1021%2Facs.jnatprod.5b00949

https://doi.org/10.1016%2Fj.tplants.2020.05.005

https://doi.org/10.1016%2Fj.pharmthera.2004.11.005

https://doi.org/10.1016%2FB978-0-12-418679-8.00013-7

https://doi.org/10.1002%2F%28SICI%291097-0320%2819990301%2935%3A3%3C227%3A%3AAID-CYTO5%3E3.0.CO%3B2-4

https://doi.org/10.1111%2Fj.1432-1033.1995.tb20780.x

https://doi.org/10.1016%2Fj.plipres.2011.01.001

https://doi.org/10.1021%2Facsptsci.9b00049

https://doi.org/10.1002%2Fsyn.20050

https://doi.org/10.1046%2Fj.1432-1327.2001.02030.x

https://doi.org/10.1016%2Fj.schres.2015.01.033

https://doi.org/10.1002%2Fcbdv.200790147

https://doi.org/10.1038%2Fsj.bjp.0707460

https://doi.org/10.1007%2Fs11064-005-6978-1

https://doi.org/10.1098%2Frstb.2011.0389

https://doi.org/10.1038%2Fnews.2010.508

https://doi.org/10.1016%2Fj.biopsych.2015.11.018

https://doi.org/10.1021%2Fjm970126f

https://doi.org/10.1021%2Facs.jnatprod.0c00965

https://doi.org/10.1038%2Fsj.bjp.0706406

https://doi.org/10.2174%2F156802608783498023

https://doi.org/10.1055%2Fs-2006-962030

https://doi.org/10.1074%2Fjbc.M601074200

https://doi.org/10.1055%2Fs-2006-957605

https://doi.org/10.1016%2FS0021-9673%2898%2900447-6

https://doi.org/10.1016%2Fj.phrs.2012.04.003

https://doi.org/10.1016%2Fj.phymed.2009.10.001

https://doi.org/10.1073%2Fpnas.0803601105

https://doi.org/10.1016%2Fj.phytochem.2014.11.012
























































































By Jason King 04 Apr, 2024
Unlocking Wellness with Magnesium Oil Spray from Servant's Hearts Natural Well-Being Products In the pursuit of optimal health, many of us recognize the importance of maintaining adequate levels of essential nutrients. However, even with a balanced diet rich in real foods, obtaining sufficient magnesium can pose a challenge. That's where magnesium oil spray comes into play, offering a convenient and effective solution to address magnesium deficiency. As the proud owner of Servant's Hearts Natural Well-Being Products, I am passionate about providing top-quality magnesium oil spray to support your journey towards wellness. Understanding the Magnesium Deficiency Dilemma Why is magnesium deficiency so prevalent despite our best efforts to maintain a healthy lifestyle? The answer lies in various factors that actively deplete our magnesium levels. From chronic stress and sleep deprivation to excessive consumption of alcohol, caffeine, and sugar, modern lifestyles often sabotage our magnesium intake. Furthermore, agricultural practices such as over-farming and pesticide use have led to depleted magnesium levels in soil, exacerbating the problem. Even water filtration systems strip away naturally occurring magnesium from our water sources. While the ocean remains a rich reservoir of magnesium and trace minerals, not everyone has daily access to its potential benefits. This underscores the importance of exploring alternative methods, such as transdermal magnesium oil application, to replenish our magnesium levels effectively. Harnessing the Power of Magnesium Oil Spray: Benefits and Beyond Magnesium plays a pivotal role in numerous biochemical reactions within the body, influencing everything from muscle and nerve function to bone health and blood sugar control. As a natural source of magnesium, our topical magnesium oil spray offers a myriad of benefits, making it a cornerstone of holistic wellness. 1. Improved Magnesium Levels Transdermal magnesium therapy, including the use of magnesium oil spray, presents a practical solution to enhance cellular magnesium levels. Research, including a 2010 study by the Herbal Research Centre, highlights the efficacy of this approach in boosting magnesium absorption, thereby serving as nutritional insurance against deficiency. 2. Enhanced Skin Health In addition to its internal benefits, magnesium oil spray promotes smoother and healthier skin. Incorporating it into your skincare routine, alongside techniques like dry brushing, can contribute to a radiant complexion and minimized breakouts. 3. Alleviation of Muscle Soreness Athletes and fitness enthusiasts alike swear by magnesium oil spray for post-workout recovery. Its ability to help reduce muscle cramping and replenish lost magnesium levels through sweat makes it a valuable companion in your fitness journey. 4. Relief from Headaches and Migraines Studies underscore the significance of magnesium in managing headaches and migraines. While not an acute treatment, maintaining optimal cellular magnesium levels may lead to a reduction in the frequency and severity of these debilitating conditions. 5. Support for Blood Sugar Regulation Research suggests a link between magnesium and balanced blood sugar levels. By addressing magnesium deficiency, individuals may contribute to a holistic approach to managing blood sugar and insulin levels, crucial for overall metabolic health. 6. Mitigation of Blood Pressure and Hypertension The benefits of magnesium supplementation extend to cardiovascular health, with studies indicating its potential to modestly reduce blood pressure levels. Incorporating both internal and transdermal magnesium supplementation may yield favorable outcomes in blood pressure management. 7. Promotion of Restful Sleep Magnesium's influence on GABA receptors in the brain underscores its role in promoting relaxation and facilitating deeper sleep. While some individuals may experience heightened awareness from magnesium supplementation, strategic timing can mitigate this effect. Harnessing the Soothing Power of Magnesium Oil Spray: Application Tips Integrating magnesium oil spray into your daily routine is not only simple but also empowering, especially when armed with key information about its magnesium content. Here's a closer look at the application tips, along with insights into the magnesium dosage provided by Servant's Hearts Natural Well-Being Products: Magnesium Content Breakdown: MG of Magnesium Chloride Flakes per 4 oz Bottle: 7,500 mg MG of Magnesium per Pump/Spray (Based on a Bottle Containing 600 Sprays):* 12.5 mg Daily MG of Magnesium if You Use 40 Pumps/Sprays per Day, as Recommended: 500 mg *Note: The number of pumps or sprays you can get from a 4 oz glass bottle sprayer depends on various factors such as the design of the sprayer, the viscosity of the liquid inside, and the size of each pump/spray. As a general guideline, a 4 oz bottle might contain anywhere from 400 to 800 pumps/sprays, assuming each pump/spray delivers around 0.05 to 0.1 ml of liquid. This is just an approximation and can vary significantly. 600 pumps/sprays is the midpoint between the 400 and 800 pump/spray per bottle estimation and what I use to calculate approximate mg per spray. Practical Application Tips: Magnesium Oil Spray Instructions: Use twice a day. Once in the morning and once at night. Morning – Spray 10 pumps on each forearm and rub in. That’s a total of 20 pumps for both arms in the morning. Evening (Before bed) – Spray 10 pumps on each hamstring (back of your thigh) and rub in. That’s a total of 20 pumps for both hamstrings each night. That’s a total of 40 pumps per day total. Spraying the pumps into the palm of your hand and rubbing it in that way, rather than spraying directly on the arms or legs, will save a lot of the spray from being wasted, especially if you have bad aim. Absorption Awareness: Upon application, you may experience a mild tingling sensation on the skin, which is normal and indicative of transdermal absorption taking place. Embrace this sensation as a sign that your body is absorbing the magnesium effectively. Customization Consideration: For individuals with sensitive skin, consider diluting the magnesium oil or adjusting the frequency of application to suit your comfort level. Gradually increase the dosage as your skin acclimates to the magnesium oil. Post-Application Protocol: Allow the magnesium oil to absorb into the skin for optimal transdermal absorption. Follow up with moisturization using coconut oil or a lotion bar to soothe the skin and minimize any residual stickiness. Consistent Usage: Incorporate magnesium oil spray into your daily wellness routine, preferably after a shower or bath when your skin is clean and receptive to absorption. Consistency is key to reaping the full benefits of magnesium supplementation. CONCLUSION By adhering to these application tips and leveraging the magnesium-rich formulation of Servant's Hearts Natural Well-Being Products, you can harness the soothing power of magnesium oil spray to support your journey towards holistic wellness. Embrace the transformative potential of magnesium and unlock a world of vitality and vitality, one spray at a time. Servant's Heart Natural Well-Being Products Please visit Servant's Heart Products (servantsheartglobal.com) for all-natural, affordable, high quality, and potent CBD products, including gummies and topical. We also carry an affordable and high quality 4 oz bottle of Magnesium Oil Spray for $12. All-natural scents available include: unscented, rosemary and lavender, frankincense and myrrh, lemon and orange, eucalyptus, and green tea and lemongrass. ADDITIONAL MAGNESIUM OIL SPRAY RESOURCES About 60% of the magnesium in your body occurs in bone, while the rest is in muscles, soft tissues, and fluids, including blood ( 1Trusted Source ). Nonetheless, studies suggest that approximately 50% of U.S. adults get less than the recommended daily amount of magnesium (1Trusted Source, 3Trusted Source ). Magnesium helps move blood sugar into your muscles and dispose of lactate, which can build up during exercise and cause fatigue ( 5Trusted Source ). In a 2019 study, professional male cyclists players who took 400 mg of magnesium per day for 3 weeks experienced improvements in muscle recovery and protection from muscle damage following a strenuous race, compared to cyclists taking a placebo ( 8Trusted Source ). Magnesium plays a critical role in brain function and mood; low levels are linked to an increased risk of depression ( 9Trusted Source ). What's more, supplementing with this mineral may help reduce symptoms of depression ( 10Trusted Source , 11Trusted Source). Additionally, research indicates that people who consume more magnesium have a lower risk of type 2 diabetes ( 13Trusted Source , 14Trusted Source). According to one review, magnesium supplements help enhance insulin sensitivity, a key factor in blood sugar control ( 15Trusted Source ). A 2021 review shows that magnesium supplements can help lower high blood pressure levels, which may be a risk factor for heart disease ( 16Trusted Source ). Another review linked high magnesium intake to a lower risk of heart disease, stroke, and high blood pressure ( 17Trusted Source ). Low magnesium intake is linked to increased levels of inflammation, which plays a crucial role in aging and chronic disease ( 20Trusted Source , 21Trusted Source). Low magnesium intake is linked to increased levels of inflammation, which plays a crucial role in aging and chronic disease (20Trusted Source, 21Trusted Source ). Furthermore, some research ties magnesium deficiency to increased oxidative stress, which is related to inflammation ( 25Trusted Source ). Migraine headaches can be painful and often cause nausea, vomiting, and sensitivity to light and noise ( 26Trusted Source ). In one older study, supplementing with 1 gram of magnesium provided relief from acute migraine attacks more quickly and effectively than a common medication ( 29Trusted Source ). Eating more magnesium-rich foods may also help reduce migraine symptoms ( 30Trusted Source ). Premenstrual syndrome (PMS) is one of the most common conditions in female-bodied people of childbearing age. It often causes symptoms such as water retention, abdominal cramps, tiredness, and irritability ( 31Trusted Source ). Some studies associate lower levels of this mineral with a higher risk of osteoporosis, which causes bones to become brittle and weak ( 36Trusted Source ). A 3-year study in 358 people undergoing hemodialysis — a treatment to help remove waste and water from the blood — showed that those who consumed the least magnesium experienced three times more fractures than those with the highest intake ( 37Trusted Source ). This is because magnesium regulates several neurotransmitters involved in sleep, such as gamma aminobutyric acid ( 39Trusted Source ). One review of older adults with insomnia found that magnesium supplements lowered the amount of time it took people to fall asleep by an average of 17 minutes ( 40Trusted Source ). Furthermore, another study associated higher magnesium intake in women with a reduced likelihood of falling asleep during the daytime ( 42Trusted Source ). If you have a medical condition, check with your doctor before taking magnesium supplements. Though these supplements are generally well tolerated, they may be unsafe for people who take certain diuretics, heart medications, osteoporosis medications, proton pump inhibitors, or antibiotics ( 47Trusted Source ). Studies show magnesium supplements may be particularly beneficial for improving exercise performance in older adults and those with a deficiency in this nutrient ( 6Trusted Source ). One older study of 2,570 women associated higher magnesium intake with increased muscle mass and power ( 7Trusted Source ). What's more, supplementing with this mineral may help reduce symptoms of depression (10Trusted Source, 11Trusted Source ). Additionally, research indicates that people who consume more magnesium have a lower risk of type 2 diabetes (13Trusted Source, 14Trusted Source ). What's more, one review found that magnesium supplements improved multiple risk factors for heart disease, including triglyceride, LDL (bad) cholesterol, HDL (good) cholesterol, and systolic blood pressure levels, especially in people with a magnesium deficiency ( 18Trusted Source ). One review of 11 studies concluded that magnesium supplements decreased levels of C-reactive protein (CRP), a marker of inflammation, in people with chronic inflammation ( 22Trusted Source ). Other studies report similar findings, showing that magnesium supplements may reduce CRP and other markers of inflammation, such as interleukin-6 ( 23Trusted Source , 24Trusted Source). Other studies report similar findings, showing that magnesium supplements may reduce CRP and other markers of inflammation, such as interleukin-6 (23Trusted Source, 24Trusted Source ). Some researchers believe that people with migraine are more likely than others to have a magnesium deficiency ( 27Trusted Source ). Several studies suggest that magnesium supplements may even prevent and treat migraine headaches ( 28Trusted Source ). Some research suggests that magnesium supplements help relieve PMS symptoms and other conditions such as menstrual cramps and migraine attacks ( 32Trusted Source ). Some research suggests that magnesium helps treat and prevent anxiety ( 43Trusted Source ). Similarly, a small 6-week study found that taking 248 mg of magnesium daily significantly reduced anxiety symptoms ( 10Trusted Source ). Other research suggests that magnesium deficiency may increase your body's susceptibility to stress, which may amplify symptoms of anxiety ( 45Trusted Source ). Al Alawi AM, Majoni SW, Falhammar H. Magnesium and human health: perspectives and research directions .Int J Endocrinol. 2018;2018:9041694. doi:10.1155/2018/9041694 Engen, Deborah J. et al. Effects of transdermal magnesium chloride on quality of life for patients with fibromyalgia: a feasibility study .Journal of Integrative Medicine. 2015;13(5):306-313. doi:10.1016/S2095-4964(15)60195-9 Sebo P, Cerutti B, Haller DM. Effect of magnesium therapy on nocturnal leg cramps: a systematic review of randomized controlled trials with meta-analysis using simulations .Fam Pract. 2014;31(1):7-19. doi:10.1093/fampra/cmt065 Chandrasekaran NC, Sanchez WY, Mohammed YH, Grice JE, Roberts MS, Barnard RT. Permeation of topically applied Magnesium ions through human skin is facilitated by hair follicles .Magnes Res. 2016;29(2):35-42. doi:10.1684/mrh.2016.0402 Kula AJ, Bansal N. Magnesium and Cardiovascular Disease in CKD: The Mysteries of a Humble Divalent Cation .Kidney Med. 2021;3(2):162-164. doi:10.1016/j.xkme.2021.02.002
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